If you've got some experience with towing in the past, you might be ready to tow something a bit larger than your average travel trailer. Most pickup trucks come with Class III trailer hitches, which are rated up to 5,000 pounds, but the pickup itself may be able to tow more than that.
To get the full towing potential out of your vehicle, you'll need a specialty hitch, such as a Class IV or a Class V. These are rated at 7,500 and 10,000 pounds, respectively. Keep in mind that your truck still needs to be rated at the appropriate towing capacity as well. There's no magical hitch out there that will allow a sedan to tow a house.
For heavier loads, look into adding trailer brakes. These are available in either surge (hydraulic) or electric models, and can help ensure that your trailer doesn't get away from you. The electric model automatically engages the brakes when it detects an incline. Meanwhile, hydraulic brakes use liquid - when the liquid shifts to a certain point, like traveling downhill, the brakes are pressed automatically.
Check with your state or local representatives for any restrictions on towing extra-heavy, oversized or wide loads. You will most likely have to clearly mark your vehicle so other motorists know to steer clear. They may also be able to tell you about any roads to avoid.